The catch
Medify Air MA-112 V3.0
Both filters carry a stated 3,000-hour life, roughly four-to-five months, and the cabinet itself is large.
Side by side
The MA-112 delivers the highest verified smoke airflow. The AD5500 is the pick if automatic sensing and a more explicit carbon/VOC filter path are worth giving up 38 CFM.
Before you buy
Of these two, only AirDoctor AD5500 Classic is confirmed for “Automatic mode”. If you need it, you have your answer.
Where this comes from
This follows directly from the checked yes-or-no difference between the exact configurations compared.
The catch
Both filters carry a stated 3,000-hour life, roughly four-to-five months, and the cabinet itself is large.
The catch
Replacements cost a lot because there are dual particle and carbon filter sets.


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Two very-high-airflow purifiers face off on smoke CADR, automation, gas filters, size and running costs.
This one comes down to smoke cadr and automatic mode first, then to the limits of your own setup.
Which one fits
Its onboard sensor can change the fan speed automatically. Check the model facts for what that sensor measures.
Regular trips from room to room are more practical thanks to its weight, handles or casters.
A mechanical filter path with no ionizer is how the exact model works.
Medify Air MA-112 V3.0 lists “594 CFM” for smoke cadr, while AirDoctor AD5500 Classic lists “556 CFM”. Extra published output only helps when your room, surface or workload needs the headroom. On its own, it does not prove better results.
In practice
Of these two, only AirDoctor AD5500 Classic is confirmed for “Automatic mode”. If you need it, you have your answer.
This follows directly from the checked yes-or-no difference between the exact configurations compared.
Medify Air MA-112 V3.0 is the better match for “I'll be moving it from room to room” and “I don't want an ionizer in it”. AirDoctor AD5500 Classic is the better match for “I want it to respond automatically”.
This lines up the current strong and useful fit ratings for the exact products. It does not roll them into one overall score.
AirDoctor AD5500 Classic meets 4 of the 4 needs this comparison is built around. Medify Air MA-112 V3.0 meets 3 and misses “I want it to respond automatically”.
The count uses the current strong and useful fit ratings for these two products. Each need counts once, with no made-up score added on top.
55 of the 70 air purifiers checked fit this need. AirDoctor AD5500 Classic makes the cut. Medify Air MA-112 V3.0 does not.
The count filters every model in the current category for a strong or useful fit on this single need.
14 of the 70 air purifiers checked handle both “I need the air cleaned up fast” and “I want it to respond automatically”. AirDoctor AD5500 Classic makes the cut. Medify Air MA-112 V3.0 does not.
You can reproduce the count by filtering the current category for models with a strong or useful fit on both needs.
Plug in your numbers
This checks hard limits only. Personal preferences are left out of the math.
594 CFM of verified clean-air delivery works out to about 14.8 air changes per hour in this room. Hitting the 5 ACH target takes 200 CFM.
556 CFM of verified clean-air delivery works out to about 13.9 air changes per hour in this room. Hitting the 5 ACH target takes 200 CFM.
This uses each model’s pollutant-specific CADR at top speed and a target of five air changes per hour. Quieter settings clean less air. Raw airflow and one-change coverage claims are never swapped in.

Medify Air, MA-112
Its main strength is unusually high verified particle airflow, delivered by a very large dual-filter cabinet that offers neither software nor a furniture-friendly size.

AirDoctor, AD5500
The large dual-filter model from AirDoctor offers high verified smoke airflow, automatic sensing and a carbon/VOC stage that is documented.
Spec by spec
| Spec | Medify Air MA-112 V3.0 | AirDoctor AD5500 Classic | In practice |
|---|---|---|---|
| Smoke CADR | 594 CFM | 556 CFM | Higher published output is useful only if your room, surface or workload calls for the extra headroom. It does not, by itself, prove better results. |
| Automatic mode | No | Yes | How many steps fall to you and how much happens automatically both come down to this. |
| Gas stage | Carbon composite | Separate carbon and VOC filters | It shows what the treatment path is built to catch or reduce, and what upkeep that requires. |
Trade-offs
By the numbers
What we found across the air purifiers we compare, plus the checked facts behind each finding.
Only 13 of the 70 models checked meet every need here: “It will be cleaning an open living area”, “Wildfire smoke makes its way inside”, “I need the air cleaned up fast”, and “I want it to respond automatically”.
13 models fit, out of 70 checkedHow we countedThe count uses each product's current fit ratings for “It will be cleaning an open living area”, “Wildfire smoke makes its way inside”, “I need the air cleaned up fast”, and “I want it to respond automatically”. A need with no documented match is not counted.
| Product | Needs it meets | Facts we checked | Sources |
|---|---|---|---|
| Medify Air MA-112 V3.0 |
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| AirDoctor AD5500 Classic |
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Ready to buy
Open either model on Amazon for the current price, customer reviews and delivery options.

Your main goal is 594-CFM smoke airflow.
See price & reviews on Amazon
You expect the fan to respond automatically.
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