The catch
ASUSTOR Nimbustor 4 Gen2
Synology's DSM applications do not come with the extra hardware.
Side by side
Four NVMe positions, more official RAM headroom and two 2.5GbE ports favor the AS5404T. The DS425+ is the choice if DSM photos and backup tools suit how you manage files. Four SATA drives fit in both, so basic hard-drive capacity is equal. The surrounding hardware and software separate them.
Before you buy
On either model, RAID 5 over four compatible 12 TB hard drives gives 36 TB before overhead. In this equal-drive example, picking ASUSTOR creates no extra hard-drive capacity and picking Synology takes none away.
Where this comes from
(4 - 1) × 12 TB = 36 TB before formatting and system overhead. Four SATA bays and RAID 5 support are common to both models.
The catch
Synology's DSM applications do not come with the extra hardware.
The catch
Just two NVMe slots, and an official RAM maximum of 6 GB.


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Four-drive NAS options, ASUSTOR AS5404T vs Synology DS425+, compared on NVMe layouts, memory headroom, network ports and the real cost of the SSD plan.
Four NVMe positions, more official RAM headroom and two 2.5GbE ports favor the AS5404T. The DS425+ is the choice if DSM photos and backup tools suit how you manage files. Four SATA drives fit in both, so basic hard-drive capacity is equal. The surrounding hardware and software separate them.
Which one fits
The same basic four-drive layout works on both.
Four slots come with ASUSTOR, against two with Synology.
Support goes up to 16 GB on ASUSTOR, while Synology's official ceiling is 6 GB.
DSM and its associated packages come with DS425+. Check the requirement of each package.
In practice
On either model, RAID 5 over four compatible 12 TB hard drives gives 36 TB before overhead. In this equal-drive example, picking ASUSTOR creates no extra hard-drive capacity and picking Synology takes none away.
(4 - 1) × 12 TB = 36 TB before formatting and system overhead. Four SATA bays and RAID 5 support are common to both models.
Four NVMe slots are needed for a plan with one two-SSD mirror for applications and another two-SSD mirror for a separate workload. The physical positions are there on AS5404T. DS425+ has just two, so it cannot build that exact all-NVMe layout internally.
2 drives for the first mirror + 2 for the second = 4 NVMe positions. AS5404T has 4 and DS425+ has 2. Checks on software and compatible drives are still needed.
Compared with DS425+, AS5404T is 25 mm narrower but 7 mm deeper. ASUSTOR may suit a tight side-by-side shelf, and Synology may suit a shallow cabinet. Neither dimension comparison counts cable and ventilation clearance.
199 - 174 = 25 mm of width difference. 230 - 223 = 7 mm of depth difference.

ASUSTOR, AS5404T
A 4-bay chassis whose fastest documented network path is 2.5 Gbps.

Synology, DS425+
A 4-bay chassis whose fastest documented network path is 2.5 Gbps.
Spec by spec
| Spec | ASUSTOR Nimbustor 4 Gen2 | Synology DiskStation DS425+ | In practice |
|---|---|---|---|
| SATA drive positions | 4 | 4 | Nominal capacity works out the same for the same equal-drive RAID layout. |
| M.2 NVMe slots | 4 | 2 | Two more physical NVMe positions are on ASUSTOR. |
| Installed / maximum memory | 4 GB / 16 GB | 2 GB / 6 GB | Look at what the actual apps require instead of only the maximum number. |
| Ethernet ports | Two 2.5GbE | One 2.5GbE and one 1GbE | A single 2.5GbE link is supported by each. More links take a suitable network configuration. |
| NVMe storage planning | Compatible NVMe storage or caching | Storage pools require Synology-verified SSDs | A physical slot does not mean any SSD you already own is supported. |
| Case width and depth | 174 × 230 mm | 199 × 223 mm | Synology is slightly shallower, and ASUSTOR is narrower. |
Trade-offs
Change of plan
Go with ASUSTOR Nimbustor 4 Gen2. Four M.2 slots are found only on AS5404T.
Go with Synology DiskStation DS425+. Four SATA bays come with the Synology workflow on DS425+.
Decision guide
The same basic storage layouts fit the four hard-drive bays on both models. ASUSTOR's extra NVMe slots and memory support count when a specific workload needs them. If what you mainly want is DSM's photo organization and backup routine, hardware capacity left unused elsewhere may matter less than that daily workflow.
Synology's current specifications allow M.2 storage pools, provided the SSDs are Synology-verified. Calling those slots cache-only would be wrong, and so would assuming any spare NVMe drive is supported. Check the exact drive and firmware before you build the budget around an SSD already in a drawer.
ASUSTOR has two 2.5GbE ports, whereas Synology pairs 2.5GbE with 1GbE. Either can serve a suitable client over one 2.5GbE path. Making good use of multiple links depends on the protocol, client and network setup. Adding the port labels together does not give a guaranteed copy speed.
By the numbers
What we found across the NAS devices we compare, plus the checked facts behind each finding.
| Product | Needs it meets | Facts we checked | Sources |
|---|---|---|---|
| ASUSTOR Nimbustor 4 Gen2 |
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| Synology DiskStation DS425+ |
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Ready to buy
Open either model on Amazon for the current price, customer reviews and delivery options.

Run four hard drives and several NVMe devices together
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Run photos, shared files and backups through DSM
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